Palladium-catalyzed regio- and enantioselective migratory allylic C(sp3)-H functionalization
Alkene isomerizations and asymmetric C–H functionalizations have been independently studied, but their combination in one protocol is uncommon. Here the authors show a palladium-catalyzed method to iteratively “walk” a terminal alkene along a carbon chain to a position next to styrenes where a soft...
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| Auteurs principaux: | , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2021
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/82a069116af54d87b0e3803940d352e1 |
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| Résumé: | Alkene isomerizations and asymmetric C–H functionalizations have been independently studied, but their combination in one protocol is uncommon. Here the authors show a palladium-catalyzed method to iteratively “walk” a terminal alkene along a carbon chain to a position next to styrenes where a soft nucleophile is added asymmetrically. |
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