Ectopic PDX-1 expression directly reprograms human keratinocytes along pancreatic insulin-producing cells fate.
<h4>Background</h4>Cellular differentiation and lineage commitment have previously been considered irreversible processes. However, recent studies have indicated that differentiated adult cells can be reprogrammed to pluripotency and, in some cases, directly into alternate committed line...
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| Main Authors: | , , , , , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2011
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| Subjects: | |
| Online Access: | https://doaj.org/article/82adb1dce3cc4c6193a704913d26fed7 |
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