Mutations Located outside the Integrase Gene Can Confer Resistance to HIV-1 Integrase Strand Transfer Inhibitors
ABSTRACT Resistance to the integrase strand transfer inhibitors raltegravir and elvitegravir is often due to well-identified mutations in the integrase gene. However, the situation is less clear for patients who fail dolutegravir treatment. Furthermore, most in vitro experiments to select resistance...
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Main Authors: | Isabelle Malet, Frédéric Subra, Charlotte Charpentier, Gilles Collin, Diane Descamps, Vincent Calvez, Anne-Geneviève Marcelin, Olivier Delelis |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2017
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Online Access: | https://doaj.org/article/82d11a1903614a4ebd56a8c4c46ce7df |
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