Assessment of intrinsic and extrinsic signaling pathway in excitotoxic retinal ganglion cell death

Abstract Excitotoxicity leads to the activation of a cytotoxic cascade that causes neuronal death. In the retina, retinal ganglion cells (RGCs) die after an excitotoxic insult. Multiple pathways have been proposed to contribute to RGC death after an excitotoxic insult, including TNF signaling, JNK a...

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Bibliographic Details
Main Authors: Berkeley K. Fahrenthold, Kimberly A. Fernandes, Richard T. Libby
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
R
Q
Online Access:https://doaj.org/article/83317f3ff5434210b4ad64e85fa607aa
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