Tyrosine 136 phosphorylation of α-synuclein aggregates in the Lewy body dementia brain: involvement of serine 129 phosphorylation by casein kinase 2
Abstract Serine 129 (S129) phosphorylation of α-synuclein (αSyn) is a central feature of Lewy body (LB) disease pathology. Although the neighboring tyrosine residues Y125, Y133, and Y136 are also phosphorylation sites, little is known regarding potential roles of phosphorylation cross-talk between t...
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Auteurs principaux: | , , , , , , |
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Format: | article |
Langue: | EN |
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BMC
2021
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Accès en ligne: | https://doaj.org/article/8339408d5c114b4fb7b233af1180672c |
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