Distinguishing between exploratory and confirmatory preclinical research will improve translation.

Preclinical researchers confront two overarching agendas related to drug development: selecting interventions amid a vast field of candidates, and producing rigorous evidence of clinical promise for a small number of interventions. We suggest that each challenge is best met by two different, complem...

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Autores principales: Jonathan Kimmelman, Jeffrey S Mogil, Ulrich Dirnagl
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/835d26b2650a48708202d848d2b3fd7d
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