Identification of copy number variation-driven molecular subtypes informative for prognosis and treatment in pancreatic adenocarcinoma of a Chinese cohort

Identification of copy number variation-driven molecular subtypes informative for prognosis and treatment in pancreatic adenocarcinoma of a Chinese cohort

Background: Pancreatic adenocarcinoma (PAAD) is one of the most lethal carcinomas, and the current histopathological classifications are of limited use in clinical decision-making. There is an unmet need to identify new biomarkers for prognosis-informative molecular subtyping and ultimately for prec...

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Autores principales: Qian Zhan, Chenlei Wen, Yi Zhao, Lu Fang, Yangbing Jin, Zehui Zhang, Siyi Zou, Fanlu Li, Ying Yang, Lijia Wu, Jiabin Jin, Xiongxiong Lu, Junjie Xie, Dongfeng Cheng, Zhiwei Xu, Jun Zhang, Jiancheng Wang, XiaXing Deng, Hao Chen, Chenghong Peng, Hongwei Li, Henghui Zhang, Hai Fang, Chaofu Wang, Baiyong Shen
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
Materias:
Pancreatic adenocarcinoma
Molecular subtyping
Copy number variations
DNA repair
Receptor tyrosine kinase signaling
Medicine
R
Medicine (General)
R5-920
Acceso en línea:https://doaj.org/article/8368ecf9a37246a68cf63c55ab565e34
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https://doaj.org/article/8368ecf9a37246a68cf63c55ab565e34

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