Characterization of mitochondrial DNA quantity and quality in the human aged and Alzheimer’s disease brain

Abstract Background Mitochondrial dysfunction is a feature of neurodegenerative diseases, including Alzheimer’s disease (AD). Changes in the mitochondrial DNA copy number (mtDNAcn) and increased mitochondrial DNA mutation burden have both been associated with neurodegenerative diseases and cognitive...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Hans-Ulrich Klein, Caroline Trumpff, Hyun-Sik Yang, Annie J. Lee, Martin Picard, David A. Bennett, Philip L. De Jager
Format: article
Langue:EN
Publié: BMC 2021
Sujets:
Tau
Accès en ligne:https://doaj.org/article/838182d8c8224a2495fb01b890d7243e
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!