Protein disorder and short conserved motifs in disordered regions are enriched near the cytoplasmic side of single-pass transmembrane proteins.

Intracellular juxtamembrane regions of transmembrane proteins play pivotal roles in cell signalling, mediated by protein-protein interactions. Disordered protein regions, and short conserved motifs within them, are emerging as key determinants of many such interactions. Here, we investigated whether...

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Autores principales: Ilias Stavropoulos, Nora Khaldi, Norman E Davey, Kevin O'Brien, Finian Martin, Denis C Shields
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
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Acceso en línea:https://doaj.org/article/8398dbb3efff4ceb8fd16c92f60947e1
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