Receptor-induced thiolate couples Env activation to retrovirus fusion and infection.
According to current models of retrovirus infection, receptor binding to the surface subunit (SU) of the envelope glycoprotein (Env) triggers a conformational change in the transmembrane subunit (TM) that mediates virus fusion to cell membranes. To understand how this occurs, we investigated the rol...
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Main Authors: | Jason G Smith, James M Cunningham |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2007
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Online Access: | https://doaj.org/article/83a121dcb80b48e1a8ee66bebac040c0 |
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