microRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells.

Animal microRNAs (miRNAs) typically regulate gene expression by binding to partially complementary target sites in the 3' untranslated region (UTR) of messenger RNA (mRNA) reducing its translation and stability. They also commonly induce shortening of the mRNA 3' poly(A) tail, which contri...

Full description

Saved in:
Bibliographic Details
Main Authors: Traude H Beilharz, David T Humphreys, Jennifer L Clancy, Rolf Thermann, David I K Martin, Matthias W Hentze, Thomas Preiss
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2009
Subjects:
R
Q
Online Access:https://doaj.org/article/83ced30232c94b3c947cf5af2fba3c4b
Tags: Add Tag
No Tags, Be the first to tag this record!