Establishment of liver tumor cell lines from atherogenic and high fat diet fed hepatitis C virus transgenic mice

Abstract A syngeneic mouse model bearing a transplanted tumor is indispensable for the evaluation of the efficacy of immune checkpoint inhibitors (ICIs). However, few syngeneic mouse models of liver cancer are available. We established liver tumor cell lines (MHCF1 and MHCF5) from hepatitis C virus...

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Main Authors: Takayoshi Shirasaki, Kazuhisa Murai, Masao Honda, Hikari Okada, Yuika Innami, Atsumu Yamada, Tetsuro Shimakami, Kazunori Kawaguchi, Taro Yamashita, Yoshio Sakai, Shuichi Kaneko
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/83d1978205734f18b3659fe9a8becfb7
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