A functional variant of the dimethylarginine dimethylaminohydrolase-2 gene is associated with insulin sensitivity.

A functional variant of the dimethylarginine dimethylaminohydrolase-2 gene is associated with insulin sensitivity.

<h4>Background</h4>Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of endothelial nitric oxide synthase, which was associated with insulin resistance. Dimethylarginine dimethylaminohydrolase (DDAH) is the major determinant of plasma ADMA. Examining data from the DIAGRAM+ (D...

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Main Authors: Francesco Andreozzi, Ivan Presta, Gaia Chiara Mannino, Daniela Scarpelli, Sara Di Silvestre, Natalia Di Pietro, Elena Succurro, Angela Sciacqua, Assunta Pandolfi, Agostino Consoli, Marta Letizia Hribal, Francesco Perticone, Giorgio Sesti
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
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Science
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Online Access:https://doaj.org/article/83f380630062439381abc3f41de6531b
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https://doaj.org/article/83f380630062439381abc3f41de6531b

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