Γ-secretase components as predictors of breast cancer outcome.

γ-secretase is a large ubiquitously expressed protease complex composed of four core subunits: presenilin, Aph1, PEN-2, and nicastrin. The function of γ-secretase in the cells is to proteolytically cleave various proteins within their transmembrane domains. Presenilin and Aph1 occur as alternative v...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Hanna M Peltonen, Annakaisa Haapasalo, Mikko Hiltunen, Vesa Kataja, Veli-Matti Kosma, Arto Mannermaa
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2013
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/83fb7fe22f0c41e89e9376c0fc15e297
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!