Information content differentiates enhancers from silencers in mouse photoreceptors

Enhancers and silencers often depend on the same transcription factors (TFs) and are conflated in genomic assays of TF binding or chromatin state. To identify sequence features that distinguish enhancers and silencers, we assayed massively parallel reporter libraries of genomic sequences targeted by...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Ryan Z Friedman, David M Granas, Connie A Myers, Joseph C Corbo, Barak A Cohen, Michael A White
Formato: article
Lenguaje:EN
Publicado: eLife Sciences Publications Ltd 2021
Materias:
R
Q
Acceso en línea:https://doaj.org/article/84316855e8ba44709990ec78c1d8425e
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!