The histone H3 lysine 27-specific demethylase Jmjd3 is required for neural commitment.

Patterns of methylation at lysine 4 and 27 of histone H3 have been associated with states of gene activation and repression that are developmentally regulated and are thought to underlie the establishment of lineage specific gene expression programs. Recent studies have provided fundamental insight...

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Autores principales: Thomas Burgold, Fabio Spreafico, Francesca De Santa, Maria Grazia Totaro, Elena Prosperini, Gioacchino Natoli, Giuseppe Testa
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2008
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Acceso en línea:https://doaj.org/article/8431b88aec124da98c71019e648380d5
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