Assumptions and properties of limiting pathway models for analysis of epistasis in complex traits.

For most complex traits, results from genome-wide association studies show that the proportion of the phenotypic variance attributable to the additive effects of individual SNPs, that is, the heritability explained by the SNPs, is substantially less than the estimate of heritability obtained by stan...

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Bibliographic Details
Main Authors: Sven Stringer, Eske M Derks, René S Kahn, William G Hill, Naomi R Wray
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
R
Q
Online Access:https://doaj.org/article/84345986f3824d699195f01655d997ab
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