Alternative-NHEJ is a mechanistically distinct pathway of mammalian chromosome break repair.

Characterizing the functional overlap and mutagenic potential of different pathways of chromosomal double-strand break (DSB) repair is important to understand how mutations arise during cancer development and treatment. To this end, we have compared the role of individual factors in three different...

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Auteurs principaux: Nicole Bennardo, Anita Cheng, Nick Huang, Jeremy M Stark
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2008
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Accès en ligne:https://doaj.org/article/8447b4238eff4c5a85124cbdf27fc4c5
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