Glucocorticoids regulation of FosB/ΔFosB expression induced by chronic opiate exposure in the brain stress system.
Chronic use of drugs of abuse profoundly alters stress-responsive system. Repeated exposure to morphine leads to accumulation of the transcription factor ΔFosB, particularly in brain areas associated with reward and stress. The persistent effects of ΔFosB on target genes may play an important role i...
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Autores principales: | , , , |
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Formato: | article |
Lenguaje: | EN |
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Public Library of Science (PLoS)
2012
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Acceso en línea: | https://doaj.org/article/847272a7053c4ab292beae5f18050042 |
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