Autophagy facilitates adaptation of budding yeast to respiratory growth by recycling serine for one-carbon metabolism

Autophagy is important during stress and development, but how the metabolites generated are used by the cell remains unclear. Here, the authors demonstrate that budding yeast require autophagy to provide serine for one-carbon metabolism during the switch from glycolytic to respiratory growth.

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Bibliographic Details
Main Authors: Alexander I. May, Mark Prescott, Yoshinori Ohsumi
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/848e8d66c68843d58e4a913ad2620fea
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Summary:Autophagy is important during stress and development, but how the metabolites generated are used by the cell remains unclear. Here, the authors demonstrate that budding yeast require autophagy to provide serine for one-carbon metabolism during the switch from glycolytic to respiratory growth.