Gene Modification and Three‐Dimensional Scaffolds as Novel Tools to Allow the Use of Postnatal Thymic Epithelial Cells for Thymus Regeneration Approaches

Gene Modification and Three‐Dimensional Scaffolds as Novel Tools to Allow the Use of Postnatal Thymic Epithelial Cells for Thymus Regeneration Approaches

Abstract Defective functionality of thymic epithelial cells (TECs), due to genetic mutations or injuring causes, results in altered T‐cell development, leading to immunodeficiency or autoimmunity. These defects cannot be corrected by hematopoietic stem cell transplantation (HSCT), and thymus transpl...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ileana Bortolomai, Monica Sandri, Elena Draghici, Elena Fontana, Elisabetta Campodoni, Genni Enza Marcovecchio, Francesca Ferrua, Laura Perani, Antonello Spinelli, Tamara Canu, Marco Catucci, Tiziano Di Tomaso, Lucia Sergi Sergi, Antonio Esposito, Angelo Lombardo, Luigi Naldini, Anna Tampieri, Georg A. Hollander, Anna Villa, Marita Bosticardo
Format: article
Langue:EN
Publié: Wiley 2019
Sujets:
3D collagen scaffolds
Lentiviral vector
Thymic epithelial cells
Thymic regeneration
Medicine (General)
R5-920
Cytology
QH573-671
Accès en ligne:https://doaj.org/article/84a5cdcf9f7d4b5e98536d3398bf01f3
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Internet

https://doaj.org/article/84a5cdcf9f7d4b5e98536d3398bf01f3

Documents similaires