Genome evolution and the emergence of pathogenicity in avian Escherichia coli

It is unclear how gut-dwelling E. coli bacteria often emerge to cause systemic infection in chickens. Here, Mageiros et al. use population genomics and pangenome-wide association studies to identify genetic elements associated with pathogenicity in avian E. coli.

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Autores principales: Leonardos Mageiros, Guillaume Méric, Sion C. Bayliss, Johan Pensar, Ben Pascoe, Evangelos Mourkas, Jessica K. Calland, Koji Yahara, Susan Murray, Thomas S. Wilkinson, Lisa K. Williams, Matthew D. Hitchings, Jonathan Porter, Kirsty Kemmett, Edward J. Feil, Keith A. Jolley, Nicola J. Williams, Jukka Corander, Samuel K. Sheppard
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/84dde1b573d54cc6b0e1ccb662ceff09
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spelling oai:doaj.org-article:84dde1b573d54cc6b0e1ccb662ceff092021-12-02T14:06:23ZGenome evolution and the emergence of pathogenicity in avian Escherichia coli10.1038/s41467-021-20988-w2041-1723https://doaj.org/article/84dde1b573d54cc6b0e1ccb662ceff092021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-20988-whttps://doaj.org/toc/2041-1723It is unclear how gut-dwelling E. coli bacteria often emerge to cause systemic infection in chickens. Here, Mageiros et al. use population genomics and pangenome-wide association studies to identify genetic elements associated with pathogenicity in avian E. coli.Leonardos MageirosGuillaume MéricSion C. BaylissJohan PensarBen PascoeEvangelos MourkasJessica K. CallandKoji YaharaSusan MurrayThomas S. WilkinsonLisa K. WilliamsMatthew D. HitchingsJonathan PorterKirsty KemmettEdward J. FeilKeith A. JolleyNicola J. WilliamsJukka CoranderSamuel K. SheppardNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Leonardos Mageiros
Guillaume Méric
Sion C. Bayliss
Johan Pensar
Ben Pascoe
Evangelos Mourkas
Jessica K. Calland
Koji Yahara
Susan Murray
Thomas S. Wilkinson
Lisa K. Williams
Matthew D. Hitchings
Jonathan Porter
Kirsty Kemmett
Edward J. Feil
Keith A. Jolley
Nicola J. Williams
Jukka Corander
Samuel K. Sheppard
Genome evolution and the emergence of pathogenicity in avian Escherichia coli
description It is unclear how gut-dwelling E. coli bacteria often emerge to cause systemic infection in chickens. Here, Mageiros et al. use population genomics and pangenome-wide association studies to identify genetic elements associated with pathogenicity in avian E. coli.
format article
author Leonardos Mageiros
Guillaume Méric
Sion C. Bayliss
Johan Pensar
Ben Pascoe
Evangelos Mourkas
Jessica K. Calland
Koji Yahara
Susan Murray
Thomas S. Wilkinson
Lisa K. Williams
Matthew D. Hitchings
Jonathan Porter
Kirsty Kemmett
Edward J. Feil
Keith A. Jolley
Nicola J. Williams
Jukka Corander
Samuel K. Sheppard
author_facet Leonardos Mageiros
Guillaume Méric
Sion C. Bayliss
Johan Pensar
Ben Pascoe
Evangelos Mourkas
Jessica K. Calland
Koji Yahara
Susan Murray
Thomas S. Wilkinson
Lisa K. Williams
Matthew D. Hitchings
Jonathan Porter
Kirsty Kemmett
Edward J. Feil
Keith A. Jolley
Nicola J. Williams
Jukka Corander
Samuel K. Sheppard
author_sort Leonardos Mageiros
title Genome evolution and the emergence of pathogenicity in avian Escherichia coli
title_short Genome evolution and the emergence of pathogenicity in avian Escherichia coli
title_full Genome evolution and the emergence of pathogenicity in avian Escherichia coli
title_fullStr Genome evolution and the emergence of pathogenicity in avian Escherichia coli
title_full_unstemmed Genome evolution and the emergence of pathogenicity in avian Escherichia coli
title_sort genome evolution and the emergence of pathogenicity in avian escherichia coli
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/84dde1b573d54cc6b0e1ccb662ceff09
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