Metformin accelerates zebrafish heart regeneration by inducing autophagy

Abstract Metformin is one of the most widely used drugs for type 2 diabetes and it also exhibits cardiovascular protective activity. However, the underlying mechanism of its action is not well understood. Here, we used an adult zebrafish model of heart cryoinjury, which mimics myocardial infarction...

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Autores principales: Fangjing Xie, Shisan Xu, Yingying Lu, Kin Fung Wong, Lei Sun, Kazi Md Mahmudul Hasan, Alvin C. H. Ma, Gary Tse, Sinai H. C. Manno, Li Tian, Jianbo Yue, Shuk Han Cheng
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/84ea43b53dcc47779a307ebbaf94cfed
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