Identification of downstream effectors of retinoic acid specifying the zebrafish pancreas by integrative genomics

Abstract Retinoic acid (RA) is a key signal for the specification of the pancreas. Still, the gene regulatory cascade triggered by RA in the endoderm remains poorly characterized. In this study, we investigated this regulatory network in zebrafish by combining RNA-seq, RAR ChIP-seq and ATAC-seq assa...

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Autores principales: Ana R. López-Pérez, Piotr J. Balwierz, Boris Lenhard, Ferenc Muller, Fiona C. Wardle, Isabelle Manfroid, Marianne L. Voz, Bernard Peers
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/850bfa32b31943dd9ae0d3bdc4010ac4
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