Expeditious diastereoselective synthesis of elaborated ketones via remote Csp3–H functionalization

C-H activation is a powerful method to form functionalised molecules, but is particularly challenging for unactivated sp3sites. Here the authors report a directing-group-free radical cascade process for converting vinyl azides and carboxylic acids to tetralone derivatives in high diastereoselectivit...

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Bibliographic Details
Main Authors: Wei Shu, Adriana Lorente, Enrique Gómez-Bengoa, Cristina Nevado
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/8554b14d36544c84abbb58a4cb4fdf3a
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