Cooperative functions of ZnT1, metallothionein and ZnT4 in the cytoplasm are required for full activation of TNAP in the early secretory pathway.

The activation process of secretory or membrane-bound zinc enzymes is thought to be a highly coordinated process involving zinc transport, trafficking, transfer and coordination. We have previously shown that secretory and membrane-bound zinc enzymes are activated in the early secretory pathway (ESP...

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Main Authors: Shigeyuki Fujimoto, Naoya Itsumura, Tokuji Tsuji, Yasumi Anan, Natsuko Tsuji, Yasumitsu Ogra, Tomoki Kimura, Yusaku Miyamae, Seiji Masuda, Masaya Nagao, Taiho Kambe
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
R
Q
Online Access:https://doaj.org/article/8569074a09b24ded9d485deda3637757
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