LIN28 is involved in glioma carcinogenesis and predicts outcomes of glioblastoma multiforme patients.

LIN28, an evolutionarily conversed RNA binding protein which can bind to the terminal loops of let-7 family microRNA precursors and block their processing to maturation, is highly expressed in several subsets of tumors that carry poor prognoses, such as ovarian carcinoma, hepatocellular carcinoma, c...

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Auteurs principaux: Rong Qin, Jingxu Zhou, Chao Chen, Tao Xu, Yong Yan, Yushui Ma, Zongli Zheng, Yiping Shen, Yicheng Lu, Da Fu, Juxiang Chen
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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Accès en ligne:https://doaj.org/article/857ce9939f284a6c98f70a123cc2756c
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