LIN28 is involved in glioma carcinogenesis and predicts outcomes of glioblastoma multiforme patients.
LIN28, an evolutionarily conversed RNA binding protein which can bind to the terminal loops of let-7 family microRNA precursors and block their processing to maturation, is highly expressed in several subsets of tumors that carry poor prognoses, such as ovarian carcinoma, hepatocellular carcinoma, c...
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Auteurs principaux: | , , , , , , , , , , |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2014
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Accès en ligne: | https://doaj.org/article/857ce9939f284a6c98f70a123cc2756c |
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