A Novel Microphysiological Colon Platform to Decipher Mechanisms Driving Human Intestinal PermeabilitySummary

A Novel Microphysiological Colon Platform to Decipher Mechanisms Driving Human Intestinal PermeabilitySummary

Background & Aims: The limited availability of organoid systems that mimic the molecular signatures and architecture of human intestinal epithelium has been an impediment to allowing them to be harnessed for the development of therapeutics as well as physiological insights. We developed a mi...

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Auteurs principaux: Athanasia Apostolou, Rohit A. Panchakshari, Antara Banerjee, Dimitris V. Manatakis, Maria D. Paraskevopoulou, Raymond Luc, Galeb Abu-Ali, Alexandra Dimitriou, Carolina Lucchesi, Gauri Kulkarni, Tengku Ibrahim Maulana, Magdalena Kasendra, Jordan S. Kerns, Bertram Bleck, Lorna Ewart, Elias S. Manolakos, Geraldine A. Hamilton, Cosmas Giallourakis, Katia Karalis
Format: article
Langue:EN
Publié: Elsevier 2021
Sujets:
Organoids
Organ-on-Chip
Leaky Gut
Interleukin 22
Diseases of the digestive system. Gastroenterology
RC799-869
Accès en ligne:https://doaj.org/article/8581303f9bfe4c679f3e7c038c1061c8
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https://doaj.org/article/8581303f9bfe4c679f3e7c038c1061c8

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