<named-content content-type="genus-species">Plasmodium berghei</named-content> K13 Mutations Mediate <italic toggle="yes">In Vivo</italic> Artemisinin Resistance That Is Reversed by Proteasome Inhibition

ABSTRACT The recent emergence of Plasmodium falciparum parasite resistance to the first line antimalarial drug artemisinin is of particular concern. Artemisinin resistance is primarily driven by mutations in the P. falciparum K13 protein, which enhance survival of early ring-stage parasites treated...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Nelson V. Simwela, Barbara H. Stokes, Dana Aghabi, Matt Bogyo, David A. Fidock, Andrew P. Waters
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2020
Materias:
K13
Acceso en línea:https://doaj.org/article/85aa674b6bf4474081ee9cbaad5abeea
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!