Probing aggrephagy using chemically-induced protein aggregates

Autophagic clearance of aggregates, aggrephagy, is essential for cellular homeostasis but tools to induce and monitor it are limited. Here the authors present a fluorescence-based aggrephagy induction assay to study spatiotemporal dynamics and control mechanisms driving protein aggregate clearance.

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Autores principales: Anne F. J. Janssen, Eugene A. Katrukha, Wendy van Straaten, Pauline Verlhac, Fulvio Reggiori, Lukas C. Kapitein
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/85ed80bc1271416392f254108752a151
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