Probing aggrephagy using chemically-induced protein aggregates

Autophagic clearance of aggregates, aggrephagy, is essential for cellular homeostasis but tools to induce and monitor it are limited. Here the authors present a fluorescence-based aggrephagy induction assay to study spatiotemporal dynamics and control mechanisms driving protein aggregate clearance.

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Autores principales:	Anne F. J. Janssen, Eugene A. Katrukha, Wendy van Straaten, Pauline Verlhac, Fulvio Reggiori, Lukas C. Kapitein
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/85ed80bc1271416392f254108752a151
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id	oai:doaj.org-article:85ed80bc1271416392f254108752a151
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spelling	oai:doaj.org-article:85ed80bc1271416392f254108752a1512021-12-02T16:50:12ZProbing aggrephagy using chemically-induced protein aggregates10.1038/s41467-018-06674-42041-1723https://doaj.org/article/85ed80bc1271416392f254108752a1512018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06674-4https://doaj.org/toc/2041-1723Autophagic clearance of aggregates, aggrephagy, is essential for cellular homeostasis but tools to induce and monitor it are limited. Here the authors present a fluorescence-based aggrephagy induction assay to study spatiotemporal dynamics and control mechanisms driving protein aggregate clearance.Anne F. J. JanssenEugene A. KatrukhaWendy van StraatenPauline VerlhacFulvio ReggioriLukas C. KapiteinNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Anne F. J. Janssen Eugene A. Katrukha Wendy van Straaten Pauline Verlhac Fulvio Reggiori Lukas C. Kapitein Probing aggrephagy using chemically-induced protein aggregates
description	Autophagic clearance of aggregates, aggrephagy, is essential for cellular homeostasis but tools to induce and monitor it are limited. Here the authors present a fluorescence-based aggrephagy induction assay to study spatiotemporal dynamics and control mechanisms driving protein aggregate clearance.
format	article
author	Anne F. J. Janssen Eugene A. Katrukha Wendy van Straaten Pauline Verlhac Fulvio Reggiori Lukas C. Kapitein
author_facet	Anne F. J. Janssen Eugene A. Katrukha Wendy van Straaten Pauline Verlhac Fulvio Reggiori Lukas C. Kapitein
author_sort	Anne F. J. Janssen
title	Probing aggrephagy using chemically-induced protein aggregates
title_short	Probing aggrephagy using chemically-induced protein aggregates
title_full	Probing aggrephagy using chemically-induced protein aggregates
title_fullStr	Probing aggrephagy using chemically-induced protein aggregates
title_full_unstemmed	Probing aggrephagy using chemically-induced protein aggregates
title_sort	probing aggrephagy using chemically-induced protein aggregates
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/85ed80bc1271416392f254108752a151
work_keys_str_mv	AT annefjjanssen probingaggrephagyusingchemicallyinducedproteinaggregates AT eugeneakatrukha probingaggrephagyusingchemicallyinducedproteinaggregates AT wendyvanstraaten probingaggrephagyusingchemicallyinducedproteinaggregates AT paulineverlhac probingaggrephagyusingchemicallyinducedproteinaggregates AT fulvioreggiori probingaggrephagyusingchemicallyinducedproteinaggregates AT lukasckapitein probingaggrephagyusingchemicallyinducedproteinaggregates
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Probing aggrephagy using chemically-induced protein aggregates

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