Pan-cancer analysis of neoepitopes

Abstract Somatic variations are frequent and important drivers in cancers. Amino acid substitutions can yield neoantigens that are detected by the immune system. Neoantigens can lead to immune response and tumor rejection. Although neoantigen load and occurrence have been widely studied, a detailed...

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Autores principales: Gabriel N. Teku, Mauno Vihinen
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/85f20b4349684b19a2c7a29692857839
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