Pyroptosis, superinfection, and the maintenance of the latent reservoir in HIV-1 infection

Abstract A long-lived reservoir of latently infected T cells prevents antiretroviral therapy from eliminating HIV-1 infection. Furthering our understanding of the dynamics of latency generation and maintenance is therefore vital to improve treatment outcome. Using mathematical models and experiments...

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Bibliographic Details
Main Authors: Dominik Wodarz, David N. Levy
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/85fef92f686d4e41b0ec6450ad12e46d
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