Pyroptosis, superinfection, and the maintenance of the latent reservoir in HIV-1 infection
Abstract A long-lived reservoir of latently infected T cells prevents antiretroviral therapy from eliminating HIV-1 infection. Furthering our understanding of the dynamics of latency generation and maintenance is therefore vital to improve treatment outcome. Using mathematical models and experiments...
Saved in:
Main Authors: | Dominik Wodarz, David N. Levy |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
|
Subjects: | |
Online Access: | https://doaj.org/article/85fef92f686d4e41b0ec6450ad12e46d |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Latently KSHV-Infected Cells Promote Further Establishment of Latency upon Superinfection with KSHV
by: Chen Gam ze Letova, et al.
Published: (2021) -
HIV-1 superinfection in women broadens and strengthens the neutralizing antibody response.
by: Valerie Cortez, et al.
Published: (2012) -
HIV-1 superinfection occurs less frequently than initial infection in a cohort of high-risk Kenyan women.
by: Keshet Ronen, et al.
Published: (2013) -
Dual infection and superinfection inhibition of epithelial skin cells by two alphaherpesviruses co-occur in the natural host.
by: Keith W Jarosinski
Published: (2012) -
HIV quasispecies dynamics during pro-active treatment switching: impact on multi-drug resistance and resistance archiving in latent reservoirs.
by: Max von Kleist, et al.
Published: (2011)