Structural basis for xenobiotic extrusion by eukaryotic MATE transporter

Structural basis for xenobiotic extrusion by eukaryotic MATE transporter

Mulitidrug and toxic compound extrusion (MATE) family transporters export xenobiotics and some plant MATE transporters are involved in secondary metabolite transport. Here, the authors present the structure of the Arabidopsis thaliana MATE transporter AtDTX14 and propose a model for eukaryotic MATE...

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Autores principales: Hirotake Miyauchi, Satomi Moriyama, Tsukasa Kusakizako, Kaoru Kumazaki, Takanori Nakane, Keitaro Yamashita, Kunio Hirata, Naoshi Dohmae, Tomohiro Nishizawa, Koichi Ito, Takaaki Miyaji, Yoshinori Moriyama, Ryuichiro Ishitani, Osamu Nureki
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/860c67708882429fa9cc802d892f52f9
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spelling oai:doaj.org-article:860c67708882429fa9cc802d892f52f92021-12-02T14:41:22ZStructural basis for xenobiotic extrusion by eukaryotic MATE transporter10.1038/s41467-017-01541-02041-1723https://doaj.org/article/860c67708882429fa9cc802d892f52f92017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01541-0https://doaj.org/toc/2041-1723Mulitidrug and toxic compound extrusion (MATE) family transporters export xenobiotics and some plant MATE transporters are involved in secondary metabolite transport. Here, the authors present the structure of the Arabidopsis thaliana MATE transporter AtDTX14 and propose a model for eukaryotic MATE transport mechanism.Hirotake MiyauchiSatomi MoriyamaTsukasa KusakizakoKaoru KumazakiTakanori NakaneKeitaro YamashitaKunio HirataNaoshi DohmaeTomohiro NishizawaKoichi ItoTakaaki MiyajiYoshinori MoriyamaRyuichiro IshitaniOsamu NurekiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Hirotake Miyauchi
Satomi Moriyama
Tsukasa Kusakizako
Kaoru Kumazaki
Takanori Nakane
Keitaro Yamashita
Kunio Hirata
Naoshi Dohmae
Tomohiro Nishizawa
Koichi Ito
Takaaki Miyaji
Yoshinori Moriyama
Ryuichiro Ishitani
Osamu Nureki
Structural basis for xenobiotic extrusion by eukaryotic MATE transporter
description Mulitidrug and toxic compound extrusion (MATE) family transporters export xenobiotics and some plant MATE transporters are involved in secondary metabolite transport. Here, the authors present the structure of the Arabidopsis thaliana MATE transporter AtDTX14 and propose a model for eukaryotic MATE transport mechanism.
format article
author Hirotake Miyauchi
Satomi Moriyama
Tsukasa Kusakizako
Kaoru Kumazaki
Takanori Nakane
Keitaro Yamashita
Kunio Hirata
Naoshi Dohmae
Tomohiro Nishizawa
Koichi Ito
Takaaki Miyaji
Yoshinori Moriyama
Ryuichiro Ishitani
Osamu Nureki
author_facet Hirotake Miyauchi
Satomi Moriyama
Tsukasa Kusakizako
Kaoru Kumazaki
Takanori Nakane
Keitaro Yamashita
Kunio Hirata
Naoshi Dohmae
Tomohiro Nishizawa
Koichi Ito
Takaaki Miyaji
Yoshinori Moriyama
Ryuichiro Ishitani
Osamu Nureki
author_sort Hirotake Miyauchi
title Structural basis for xenobiotic extrusion by eukaryotic MATE transporter
title_short Structural basis for xenobiotic extrusion by eukaryotic MATE transporter
title_full Structural basis for xenobiotic extrusion by eukaryotic MATE transporter
title_fullStr Structural basis for xenobiotic extrusion by eukaryotic MATE transporter
title_full_unstemmed Structural basis for xenobiotic extrusion by eukaryotic MATE transporter
title_sort structural basis for xenobiotic extrusion by eukaryotic mate transporter
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/860c67708882429fa9cc802d892f52f9
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