A small-molecule DS44170716 inhibits Ca2+-induced mitochondrial permeability transition

Abstract Mitochondria are involved in a variety of physiological and pathological processes. Ca2+ uptake is one of the important functions of the organelle for maintenance of cellular Ca2+ homeostasis. In pathological conditions such as ischemia reperfusion injury, Ca2+ overload into mitochondria in...

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Auteurs principaux: Naohiro Kon, Atsushi Satoh, Naoki Miyoshi
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/862a9fb61a6b4d48934af82cecd9a49a
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