Distinct transcriptional roles for Histone H3-K56 acetylation during the cell cycle in Yeast

H3K56Ac promotes nucleosome turnover at promoter-proximal locations and assembly of new nucleosomes during S phase. Here the authors find that H3K56Ac is both a genome-wide activator of transcription in yeast while also repressing promiscuous transcription that occurs after replication fork passage.

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Autores principales: Salih Topal, Pauline Vasseur, Marta Radman-Livaja, Craig L. Peterson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/8648fdacb8d442c6b28968ce368848df
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