Revealing the mechanisms of membrane protein export by virulence-associated bacterial secretion systems

Many bacteria export effector proteins even when two incompatible signal sequences are present, one which would lead to export and the other to inner membrane targeting. Here the authors show that such proteins feature decreased hydrophobicity or cognate chaperone binding to prevent erroneous target...

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Autores principales: Lea Krampen, Silke Malmsheimer, Iwan Grin, Thomas Trunk, Anja Lührmann, Jan-Willem de Gier, Samuel Wagner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/864e25c152e74479baf43777512bbf77
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