Clinically Relevant Mutations of Mycobacterial GatCAB Inform Regulation of Translational Fidelity
ABSTRACT Most bacteria employ a two-step indirect tRNA aminoacylation pathway for the synthesis of aminoacylated tRNAGln and tRNAAsn. The heterotrimeric enzyme GatCAB performs a critical amidotransferase reaction in the second step of this pathway. We have previously demonstrated in mycobacteria tha...
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Autores principales: | Yang-Yang Li, Rong-Jun Cai, Jia-Ying Yang, Tamara L. Hendrickson, Ye Xiang, Babak Javid |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/8667954f6d2a4905887e75541bdb280d |
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