Progression of mouse skin carcinogenesis is associated with increased ERα levels and is repressed by a dominant negative form of ERα.

Progression of mouse skin carcinogenesis is associated with increased ERα levels and is repressed by a dominant negative form of ERα.

Estrogen receptors (ER), namely ERα and ERβ, are hormone-activated transcription factors with an important role in carcinogenesis. In the present study, we aimed at elucidating the implication of ERα in skin cancer, using chemically-induced mouse skin tumours, as well as cell lines representing dist...

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Main Authors: Stella Logotheti, Dimitra Papaevangeliou, Ioannis Michalopoulos, Maria Sideridou, Katerina Tsimaratou, Ioannis Christodoulou, Katerina Pyrillou, Vassilis Gorgoulis, Spiros Vlahopoulos, Vassilis Zoumpourlis
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/866cb55984d54136a886fcc3e806aa39
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https://doaj.org/article/866cb55984d54136a886fcc3e806aa39

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