MiR-191-5p alleviates microglial cell injury by targeting Map3k12 (mitogen-activated protein kinase kinase kinase 12) to inhibit the MAPK (mitogen-activated protein kinase) signaling pathway in Alzheimer’s disease: Running Title: Role of miR-191-5p in Alzheimer’s disease

MiR-191-5p alleviates microglial cell injury by targeting Map3k12 (mitogen-activated protein kinase kinase kinase 12) to inhibit the MAPK (mitogen-activated protein kinase) signaling pathway in Alzheimer’s disease: Running Title: Role of miR-191-5p in Alzheimer’s disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disease. Multiple reports have elucidated that microRNAs are promising biomarkers for AD diagnosis and treatment. Herein, the effect of miR-191-5p on microglial cell injury and the underlying mechanism were explored. APP/PS1 transgenic mice...

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Autores principales: Wenjun Wan, Ganzhe Liu, Xia Li, Yu Liu, Ying Wang, Haisong Pan, Jun Hu
Formato: article
Lenguaje:EN
Publicado: Taylor & Francis Group 2021
Materias:
alzheimer’s disease
mir-191-5p
map3k12
microglia
mapk signaling
Biotechnology
TP248.13-248.65
Acceso en línea:https://doaj.org/article/86808bc2de7e4cd59af49aca62e20d8a
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https://doaj.org/article/86808bc2de7e4cd59af49aca62e20d8a

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