The Orai-1 and STIM-1 complex controls human dendritic cell maturation.

Ca(2+) signaling plays an important role in the function of dendritic cells (DC), the professional antigen presenting cells. Here, we described the role of Calcium released activated (CRAC) channels in the maturation and cytokine secretion of human DC. Recent works identified STIM1 and Orai1 in huma...

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Autores principales: Romain Félix, David Crottès, Anthony Delalande, Jérémy Fauconnier, Yvon Lebranchu, Jean-Yves Le Guennec, Florence Velge-Roussel
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/869032f1d1e048c2831b3102cc74b2e6
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