Prognostic Values of G-Protein Mutations in Metastatic Uveal Melanoma

Prognostic Values of G-Protein Mutations in Metastatic Uveal Melanoma

Uveal melanoma is the most common primary ocular malignancy in adults, characterized by gene mutations in G protein subunit alpha q (<i>GNAQ</i>) and G protein subunit alpha 11 (<i>GNA11</i>). Although they are considered to be driver mutations, their role in MUM remains elus...

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Autores principales: Mizue Terai, Ayako Shimada, Inna Chervoneva, Liam Hulse, Meggie Danielson, Jeff Swensen, Marlana Orloff, Philip B. Wedegaertner, Jeffrey L. Benovic, Andrew E. Aplin, Takami Sato
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
uveal melanoma
metastasis
metastatic uveal melanoma
survival
<i>GNA11</i>
<i>GNAQ</i>
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Acceso en línea:https://doaj.org/article/86a4c271f81742bab04b74ded1bf5119
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https://doaj.org/article/86a4c271f81742bab04b74ded1bf5119

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