Identification of the effector domain of biglycan that facilitates BMP-2 osteogenic function

Identification of the effector domain of biglycan that facilitates BMP-2 osteogenic function

Abstract We have reported that recombinant biglycan (BGN) core protein accelerates bone formation in vivo by enhancing bone morphogenetic protein (BMP)-2 function. The purpose of the present study was to identify the specific domain (“effector”) within the BGN core protein that facilitates BMP-2 ost...

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Autores principales: Prapaporn Jongwattanapisan, Masahiko Terajima, Patricia A. Miguez, William Querido, Hideaki Nagaoka, Noriko Sumida, Elizabeth Grace Gurysh, Kristy M. Ainslie, Nancy Pleshko, Lalith Perera, Mitsuo Yamauchi
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/86b12ac6f51546d392392532a8bb8bf5
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https://doaj.org/article/86b12ac6f51546d392392532a8bb8bf5

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