Mechanistically informed non-invasive peripheral nerve stimulation for peripheral neuropathic pain: a randomised double-blind sham-controlled trial

Mechanistically informed non-invasive peripheral nerve stimulation for peripheral neuropathic pain: a randomised double-blind sham-controlled trial

Abstract Background Induction of long-term synaptic depression (LTD) is proposed as a treatment mechanism for chronic pain but remains untested in clinical populations. Two interlinked studies; (1) A patient-assessor blinded, randomised, sham-controlled clinical trial and (2) an open-label mechanist...

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Autores principales: Selina Johnson, Anne Marshall, Dyfrig Hughes, Emily Holmes, Florian Henrich, Turo Nurmikko, Manohar Sharma, Bernhard Frank, Paul Bassett, Andrew Marshall, Walter Magerl, Andreas Goebel
Formato: article
Lenguaje:EN
Publicado: BMC 2021
Materias:
Peripheral nerve stimulation
Peripheral neuropathic pain
Long term depression
Chronic pain
Low frequency
Medicine
R
Acceso en línea:https://doaj.org/article/86be584b4caf43d598f28508c0bc0b20
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https://doaj.org/article/86be584b4caf43d598f28508c0bc0b20

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