Let-7a suppresses Ewing sarcoma CSCs’ malignant phenotype via forming a positive feedback circuit with STAT3 and lin28

Cancer stem cells (CSCs) have been documented to be closely related with tumor metastasis and recurrence, and the same important role were identified in Ewing Sarcoma (ES). In our previous study, we found that let-7a expression was repressed in ES. Herein, we further identified its putative effects...

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Auteurs principaux: Jiang Xu, Zhongzu Zhang, Lu Huang, Jiachao Xiong, Zhenhai Zhou, Honggui Yu, Liang Wu, Zhimin Liu, Kai Cao
Format: article
Langue:EN
Publié: Elsevier 2021
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Accès en ligne:https://doaj.org/article/86d85b06ad044546b9b2d8019234e2f8
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