Peritoneal tissue-resident macrophages are metabolically poised to engage microbes using tissue-niche fuels

Tissue-resident marcophages have both generic and tissue-specific functions, but how the latter functions are imbued is still unclear. Here the authors show that peritoneal macrophages express a specialised genetic programme to utilise the locally enriched glutamate for a metabolic setting that faci...

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Auteurs principaux: Luke C. Davies, Christopher M. Rice, Erika M. Palmieri, Philip R. Taylor, Douglas B. Kuhns, Daniel W. McVicar
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Accès en ligne:https://doaj.org/article/86ef4b42bcbf4bb9ae3a3b8087faf78b
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