Mechanisms of drug interactions between translation-inhibiting antibiotics

Antibiotics targeting protein translation interact in hard-to-predict ways. Here, Kavčič et al. interpret these interactions in terms of translation bottlenecks, the kinetics of drug uptake and target binding, bacterial growth laws, and a model of queued traffic progression.

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Detalles Bibliográficos
Autores principales: Bor Kavčič, Gašper Tkačik, Tobias Bollenbach
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/86f5aab737f64934aa1e07c0896df11f
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