Mechanisms of drug interactions between translation-inhibiting antibiotics
Antibiotics targeting protein translation interact in hard-to-predict ways. Here, Kavčič et al. interpret these interactions in terms of translation bottlenecks, the kinetics of drug uptake and target binding, bacterial growth laws, and a model of queued traffic progression.
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Main Authors: | Bor Kavčič, Gašper Tkačik, Tobias Bollenbach |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
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Online Access: | https://doaj.org/article/86f5aab737f64934aa1e07c0896df11f |
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