Characterization of acid sphingomyelinase activity in human cerebrospinal fluid.

<h4>Background</h4>As a key enzyme in sphingolipid metabolism, acid sphingomyelinase (ASM) is involved in the regulation of cell fate and signaling via hydrolysis of sphingomyelin to form ceramide. While increased activity of the lysosomal form has been associated with various pathologic...

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Autores principales: Christiane Mühle, Hagen B Huttner, Silke Walter, Martin Reichel, Fabio Canneva, Piotr Lewczuk, Erich Gulbins, Johannes Kornhuber
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/86f8450dfff845e0a0c455892811ea34
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